Synthesis of p-Hydroxybenzoic Acid and Salicylic Acid from Alkali Phenoxides in N,N-Dimethylformamide (1)
نویسندگان
چکیده
In a previous report, the synthesis of p-hydroxybenzoic acid and salicylic acid from alkali phenoxides and carbon dioxide in aprotic-polar solvents was reported. In the present study, the effects of reaction conditions on the yields and the rule of orientation under atmospheric pressure were examined in a typical aprotic-polar solvent, N,N-dimethylfomamide. Stabilities of the alkali salts of p-hydroxybenzoic acid and salicylic acid in the solvent were also tested. It was found that the potassium and sodium salicylates were rather stable, whereas the salts of p-hydroxybenzoic acid, except its dipotassium salt, were rather unstable and readily decomposed into phenol and carbon dioxide.
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